Catching crumbs from the table
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چکیده
منابع مشابه
Crumbs turns the corner
rumbs (Crb) helps flies distinguish apical from basal in their epithelia. Now two new studies show that it is required for cell expansion independently of its specification of apical polarity. During cell expansion, the apical domain of photoreceptors elongates perpendicular to the apical–basal axis so that the domain can extend from the top to the bottom of the fly eye. The process may be cons...
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The evolutionarily conserved Crumbs protein complex is a key regulator of cell polarity and cell shape in both invertebrates and vertebrates. The important role of this complex in normal cell function is illustrated by the finding that mutations in one of its components, Crumbs, are associated with retinal degeneration in humans, mice and flies. Recent results suggest that the Crumbs complex pl...
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ژورنال
عنوان ژورنال: Nature
سال: 2000
ISSN: 0028-0836,1476-4687
DOI: 10.1038/35014679